High doses are used most often by patients with diseases they can beat, like cancer. Rick Simpson, RSO’s developer, claims that most diseases can be beaten with 60 grams of oil. Afterwards patients can drop down to maintenance doses of a gram or so per month. For those with chronic conditions, a “BB” size dose every night is appropriate. Many of our customers start High THC RSO with a piece half the size of a grain of rice and increase as tolerated if needed.